A review paper on segmentation of positron emission tomography (PET) images

Our new article – a review piece, was recently published in “computers in biology and medicine” journal.  We systematically review the state of the art PET image segmentation methods in the literature as well as recent development in the molecular image processing domain.

Here is the article abstract. Enjoy it!
Abstract

Positron Emission Tomography (PET), a non-invasive functional imaging method at the molecular level, images the distribution of biologically targeted radiotracers with high sensitivity. PET imaging provides detailed quantitative information about many diseases and is often used to evaluate inflammation, infection, and cancer by detecting emitted photons from a radiotracer localized to abnormal cells. In order to differentiate abnormal tissue from surrounding areas in PET images, image segmentation methods play a vital role; therefore, accurate image segmentation is often necessary for proper disease detection, diagnosis, treatment planning, and follow-ups. In this review paper, we present state-of-the-art PET image segmentation methods, as well as the recent advances in image segmentation techniques. In order to make this manuscript self-contained, we also briefly explain the fundamentals of PET imaging, the challenges of diagnostic PET image analysis, and the effects of these challenges on the segmentation results.
KeywordsImage segmentationPETSUVThresholdingPET-CTMRI-PET;Review
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